Effects of toxaphene on hepatic enzyme induction and circulating steroid levels in the rat.
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چکیده
منابع مشابه
Effects of toxaphene on hepatic enzyme induction and circulating steroid levels in the rat.
Rats were given a single dose of toxaphene (120 mg/kg, equivalent to 1/2 LD50) and sacrificed at 1, 5, and 15 days. Liver weight and hepatic microsomal enzyme activity were increased at day 5 and 15. The level of plasma testosterone was significantly decreased at day 15. In a second experiment rats were given 2.4 mg/kg daily and sacrificed at 1, 3 and 6 months. Liver weight and microsomal enzym...
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ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 1976
ISSN: 0091-6765,1552-9924
DOI: 10.1289/ehp.7613117